Primary Benefits:
· Promotes normal red blood cell formation
· B-vitamins are essential for many key functions in the body
· Deficiencies in folic acid, vitamin B12, vitamin B6 or biotin may result in feelings of fatigue
· Helps decrease the effects of stress and improve mood
· Helps increase energy
· Involved in the metabolism of proteins, fats and carbohydrates
· Meets need for B-vitamins in a vegetarian diet
· Promotes cardiovascular health
· Promotes normal cognitive performance
· Vitamin B12 and folic acid provide dietary support for a healthy neuro-system and for the formation of nucleic acids and nucleic proteins. Vitamin B5 is essential in producing, transporting and releasing energy from fats
· Vitamin B6 is essential for amino acid metabolism
· Vitamins B1, B2, B3 and biotin participate in different aspects of energy production
Key Ingredients:
Vitamin B12
Vitamin B12, a bacterial product, is naturally found in organ meats, liver, beef, pork, eggs, whole milk, cheese, whole wheat bread and fish. Vitamin B12 can only be found in animal products, with small amounts derived from the fermented soy products miso and tempeh, and peanuts. It is essential that vegetarians consume a vitamin B12 supplement to maintain optimal health. Vitamin B12, when ingested, is stored in the liver and other tissues for later use. The synthetic form of B12, cyanocobalamin, is not derived from either plants or animals and is intrinsic in the maintenance of normal functioning body cells. Vitamin B12 participates in the metabolism of energy and helps maintain skin health. It is also a great anti-aging ingredient and works to help increase concentration.
Folic Acid
Folic acid is mainly found in fruits and vegetables. Dark, leafy greens, oranges, orange juice, beans and peas are the best sources, as well as Brewer’s yeast, which supply additional B-vitamins. Folic acid plays a key role by boosting the benefits of B12 supplementation. These two B-vitamins join forces and work together in helping maintain normal red blood cells. Folic acid is a component of co-enzymes. It participates in the formation of nucleic acid and nucleic protein. Scientific studies have found that when working in tandem with folic acid, B12 is capable of promoting normal homocysteine levels. This works toward supporting a healthy cardiovascular and nervous system.
Vitamin B2
Vitamin B2 is a found in liver, dairy products, dark green vegetables and some types of seafood. Vitamin B2 serves as a co-enzyme, working with other B-vitamins. It promotes healthy red blood cell formation, supports the nervous system, respiration, antibody production and normal human growth. It supports healthy skin, nails, hair growth and helps regulate thyroid activity. Vitamin B2 plays a crucial role in turning food into energy as a part of the electron transport chain, driving cellular energy on the micro-level. Riboflavin can be useful for pregnant or lactating women, as well as athletes due to their higher caloric needs. Vitamin B2 aids in the breakdown of fats while functioning as a cofactor or helper in activating B6 and folic acid. Vitamin B2 is water-soluble and cannot be stored by the body except in insignificant amounts. It must be replenished daily.
Vitamin B6
Poultry, fish, whole grains and bananas are the main dietary sources of vitamin B6. Vitamin B6 is a co-factor required for protein and amino acid metabolism and helps maintain proper fluid balance. It participates in the metabolism of amino acids. It helps with the conversion of tryptophan into Niacin Equivalent. Vitamin B6 is involved in the synthesis of neurotransmitters in the brain and peripheral nerve cells, it has been recommended as a nutrient to enhance mental function, specifically mood, and it supports nerve conduction. Some athletic supplements include vitamin B6 because it aids in the conversion of glycogen to glucose for energy in muscle tissue. Vitamin B6, when taken with folic acid, has been shown to help maintain normal plasma levels of homocysteine, which promotes cardiovascular health. Vitamin B6 should be administered as a part of a complex of other B-vitamins for best results.
Magnesium
Foods rich in magnesium include unpolished grains, nuts and green vegetables. Green, leafy vegetables are potent sources of magnesium because of their chlorophyll content. Meats, starches, milk, refined and processed foods contain low amounts of magnesium. Magnesium is a component of the mineralized part of bone, and is necessary for the metabolism of potassium and calcium in adults. It helps maintain normal levels of potassium, phosphorus, calcium, adrenaline and insulin. It’s also important for transporting calcium inside the cell for utilization. Magnesium participates in the metabolism of sugar. It helps to maintain the normal functions of the cardiovascular system, muscles and nerves, together with sodium, potassium and calcium.
Magnesium participates in energy release, regulation of the body temperature, proper nerve function, helping the body handle stress and regulating metabolism. Importantly, magnesium is also used by the body to build healthy bones, teeth and normal muscle development. It works together with calcium and vitamin D to help keep bones strong.
Potassium
Potassium is an electrolyte stored in the muscles. Foods rich in potassium include bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery. Potassium is an essential macro-mineral that helps maintain fluid balance in the body. Potassium, in the body, is classified as an electrolyte and is involved in electrical and cellular functions in the body. Among other things, potassium is important in the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, the production of energy, the synthesis of nucleic acids, and the maintenance of intracellular tonicity.
Vitamin B1
Thiamin plays an important role in carbohydrate metabolism and nerve function. Thiamin is needed for a healthy nervous system, and assists in the production of the neurotransmitter acetylcholine and gamma-aminobutyric acid (GABA). It is used in the manufacture of hydrochloric acid and, therefore, plays a part in digestion, participates in the metabolism of energy and helps promote mental clarity. Thiamin also helps maintain the normal function of the neuro and cardiovascular systems.
Pantothenate (Vitamin B5)
Pantothenic acid (B5) is the transfer agent for Choline to acetylcholine, which aids in proper neurotransmitter activity in the brain. Pantothenic acid is used in the release of energy, as well as in the metabolism of fats, proteins and carbohydrates.
Niacinamide (Vitamin B3)
Niacin is a water-soluble vitamin necessary for many aspects of health, growth and reproduction. It is part of the vitamin B complex. Niacin assists in the functioning of the digestive and nervous systems, as well as helps maintain healthy skin. It is also important for the conversion of food to energy. Niacin (also known as vitamin B-3) is found in dairy products, poultry, fish, lean meats, nuts and eggs, as well as legumes and enriched breads and cereals.
Biotin
Biotin can be found in food sources such as egg yolks, peanuts, beef liver, milk, cereals, almonds and Brewer’s yeast. Biotin takes part in healthy cell growth, the production of fatty acids, and the metabolism of fats and amino acids. It plays a role in the Citric acid cycle, which is the process in which biochemical energy is generated during aerobic respiration. Biotin not only assists in various metabolic chemical conversions, but also helps to transfer carbon dioxide. Biotin is often recommended for strengthening hair and nails.
In the News:
The Importance of the B12 Vitamin
By Tony Luck
http://www.nutritionatoz.com
Vegetarian Source of Vitamin B12
By: Alan R. Gaby
SOURCES: Townsend Letter for Doctors and Patients, May 2003 p32(1)
Vegetarian source of vitamin B12.
Looking for a Memory Pill?
By: Holly McCord, RD
Source: Amer. Jour. of Clinical Nutrition, Feb 2000.
Vegetarian and Pregnant?
By: Gloria McVeigh
Source: Prevention Nutrition News Editor, 2006
B Vitamins to Lower Homocysteine May Help Lower Stroke Risk
prohealth.com 03-27-2006
Source: Decision News © Copyright DecisionNewsMedia SAS 2006
Stroke and Broken Bones
By: Elizabeth Querna 3/2/05
Source: USNews.com
Vitamin B6, B12 and Folic Acid: Provocative New Findings
New Research on B Vitamins' Possible Relationship to Cognitive Health and Blood Sugar
By:Karen Kaufman, MS, CCN
Source: www.vrp.com
Scientific Studies:
· Benton D., et al. Thiamine supplementation for mood and cognitive functioning. Psychopharmacology. 129(1):66-71, 1997.
· Benton, D., et al. The effects of nutrients on mood. Public Health Nutr. 2(3A):403-409, 1999.
· Bhagavan, H. N., et al. The effect of pyridoxine hydrochloride on blood serotonin and pyridoxal phosphate contents in hyperactive children. Pediatrics. 55(3):437-441, 1975.
· Bronstrup A, Hages M, Prinz-Langenohl R, Pietrzik K. Effects of folic acid and combinations of folic acid and vitamin B12 on plasma homocysteine concentrations in healthy young women. Am J Clin Nutr 68:1104-10, 1998.
· Bryan, J., et al. Associations between dietary intake of folate and vitamins B-12 and B-6 and self-reported cognitive function and psychological well-being in Australian men and women in midlife. J Nutr Health Aging. 8(4):226-232, 2004.
· Bryan, J., et al. Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. Journal of Nutrition. 132(6):1345-1356, 2002.
· Coppen, A., et al. Plasma folate and affective morbidity during long-term lithium therapy. Br J Psychiatry. 141:87-89, 1982.
· Dharmarajan, T. S., et al. Vitamin B12 deficiency. Recognizing subtle symptoms in older adults. Geriatrics. 58(3):30-34, 2003.
· Duthie, S. J., et al. Homocysteine, B vitamin status, and cognitive function in the elderly. American Journal of Clinical Nutrition. 75(5):908-913, 2002.
· Grant, J. E., et al. Analysis of dietary intake and selected nutrient concentrations in patients with chronic fatigue syndrome. J Am Diet Assoc. 96(4):383-386, 1996.
· Hartvig, P., et al. Pyridoxine effect on synthesis rate of serotonin in the monkey brain measured with position emission tomography. Neural Trans. 102:91-97, 1995.
· Heap, L. C., et al. Vitamin B status in patients with chronic fatigue syndrome. J R Soc Med. 92(4):183-185, 1999.
· Heseker, H., et al. Psychological disorders as early symptoms of a mild-to-moderate vitamin deficiency. Ann N Y Acad Sci. 669:352-357, 1992.
· Jacobson, W., et al. Serum folate and chronic fatigue syndrome. Neurology. 43:2645-2647, 1993.
· Kelly, G. S. Nutritional and botanical interventions to assist with the adaptation to stress. Alternative Medicine Review.4 (4):249-265, 1999.
· Litoff, D., et al. Effects of pantothenic acid supplementation on human exercise. Med Sci Sport Exercise. 17(Supplement):287, 1985.
· Osada, K., et al. Experimental study of fatigue provoked by biotin deficiency in mice. Int J Vitam Nutr Res. 74(5):334-340, 2004.
· Riggs, K. M., et al. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition. 63(3):306-314, 1996.
· van Oort FV, Melse-Boonstra A, Brouwer IA, et al. Folic acid and reduction of plasma homocysteine concentrations in older adults: a dose-response study. 77:1318-23, 2003.
· Vargiu, R., et al. Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q(10), nicotinamide, riboflavin and pantothenic acid in the rat. Physiol Behav. 76(2):257-63, 2002.
· Wald DS, Bishop L, Wald NJ, et al. Randomized trial of folic acid supplementation and serum homocysteine levels. Arch Intern Med 61:695-700, 2001.
· Werbach, M. R. Nutritional strategies for treating chronic fatigue syndrome. Alternative Medicine Review. 5(2):93-108, 2000.
· Woo, K. S., et al. Long-term improvement in homocysteine levels and arterial endothelial function after 1-year folic acid supplementation. American Journal of Medicine. 112(7):535-539, 2002.
What Makes This Product Unique?
The two most important components when searching for the best nutritional supplements are absorption and potency. Isotonix® is unparalleled in these areas. Isotonix dietary supplements, when appropriately mixed with water, have a similar pH and osmotic pressure as some of the body’s fluids such as tears and plasma. In order for meaningful absorption of nutritional content to take place, all food must be converted into an isotonic state. In the GI tract, Isotonix experiences minimal dilution. This allows for superior delivery and maximum absorption of the most potent formulations through the Isotonix unique delivery system.
Isotonix Advanced B-Complex is an isotonic-capable combination of the essential B vitamins with magnesium and potassium, which work synergistically to promote a myriad of health benefits and biological processes in the body. B-Complex is set apart from other vitamins in terms of competing for absorption due to its being a relatively large, charged molecule. B-Complex is a water-soluble vitamin and is non-toxic. Isotonix B-Complex goes a step further in providing the proper amounts of vitamin B-12, B2 (riboflavin), B6, folic acid, vitamins B3 (niacin), B5, B1 and biotin. They work in a team effort. Vitamin B12 is not synthesized from either plants or animals. Folic acid works along with B12 to help the body break down, use and create new proteins. Vitamin B5 is involved in the energy production and is needed to make the neurotransmitter acetylcholine, as well as producing, transporting and releasing energy from fats. Thiamin, riboflavin, niacin, and biotin participate in different aspects of energy production. One can fully place their confidence in Isotonix B-Complex due to its unique delivery system that works synergistically with the body’s natural design for nutrient absorption, making sure you receive maximum health benefits.
Isotonix Advanced B-Complex works to promote healthy red blood cell formation, help increase energy, promote normal cognitive performance, promote cardiovascular health, help decrease the effects of stress and help improve mood. B vitamins are necessary for proper functioning of the nervous system, bone marrow and intestinal tract. Because many vegetarian diets are lacking in the essential B-vitamins, Isotonix B-Complex meets the need for B-vitamins for vegetarians.
Frequently Asked Questions:
What is Isotonix Advanced B-Complex?
Isotonix Advanced B-Complex is a blend of all B-vitamins with potassium and biotin. Because of the isotonic state of this blend, one can be sure that the maximum amounts of nutrients are reaching their target areas with utmost efficiency. An isotonic solution is one that actually matches the body’s own osmolarity and is easily absorbed into one’s system. Other isotonic solutions of the body include tears, plasma, and mother’s milk. These all-star B-vitamins join in the proper amounts for maximal utilization and absorption. B12 and the other B-vitamins act as members of a team. When taken all together, B12 acts as a key player in the production of energy, maintenance of healthy nerve cells and promotion of normal nervous system functioning. Folic acid is also present, playing an integral role in aiding B12 in the healthy utilization of amino acids and proteins.
What is the source of the vitamin B12 in our Isotonix Advanced B-Complex?
Vitamin B12 is a bacterial product, not synthesized by plants or animals. We get it by taking supplements or by eating eggs or meats. Vegetarians are recommended to take a B vitamin dietary supplement.
Can a person who lacks Intrinsic Factor and has to take B12 shots get benefits from taking Isotonix Advanced B-Complex?
No. Vitamin B12 requires intrinsic factor, a B12 binding protein synthesized in stomach parietal cells for proper absorption.
Why are B-vitamins so important in the aging process?
The ability to absorb B-vitamins naturally decreases with age, and various indicators of cognitive impairment are associated with reduced B-vitamin levels. The elderly in general suffer from a reduction in sense of taste and, thus, appetite and may use many acid reducing medicines that predispose them to B12 deficiency. According to Robert M. Russell of the U.S. RDA’s Human Nutrition Center on Aging at Tufts University, vitamin B12 is probably the single most important nutrient adversely affected by aging. Vitamin B12 is at once an incredibly difficult nutrient to assimilate and digest, as well as one of the most important vitamins for a broad range of bodily functions, including optimal functioning of the nervous system, normal DNA and RNA synthesis, optimal energy production and healthy blood integrity.
Is there a certain time to take B-Complex?
Isotonix Advanced B-Complex can be taken along with any of the other Isotonix products on an empty stomach. Individuals who have normal mechanisms for absorbing vitamin B12 from the gut can use Isotonix Advanced B-Complex. That is, the necessary intrinsic factors, as well as gastric functioning, must be intact for the supplement to be effective.
I am young and healthy. Why should I take B-Complex?
Health experts estimate that one in five adults is deficient in one of the B-vitamins. Absorption of vitamin B12 is a complex process, which can lead to B12 deficiency. Keep in mind that even in a healthy person’s gastrointestinal tract, there are always other proteins and vitamins competing for absorption alongside vitamin B12, which is so large and complex that it very often must struggle for entrance into the bloodstream. Specifically at risk for deficiency are vegetarians, heavy drinkers, those who take a lot of prescription or over-the-counter drugs, those with digestive disorders, pernicious anemia, recipients of gastric bypass surgery and those with poor diets. A vitamin B-complex is great for athletes, especially endurance athletes who need a natural boost of energy before a workout, due to its beneficial effects promoting the oxygenation of red blood cells.
Is it toxic to take too much vitamin B12?
Studies have found no confirmed reports of toxic side effects from heightened dosages of vitamin B12. However, you should only take Isotonix B-Complex as directed on the bottle.
Are there any warnings or contraindications for Isotonix Advanced B-Complex?
No. Isotonix Advanced B-Complex is a vegetarian product and contains no wheat, gluten, soy, yeast, artificial flavor, starch, salt, preservatives or milk.
How do I take Isotonix Advanced B-Complex?
Pour one (1) level bottle capful of powder into the overcap. Add water to the line on the overcap (60 ml/2 fl. oz.). Best when taken on an empty stomach. This product is isotonic only if the specified amounts of powder and water are used.